CCR10 rabbit pAb
Product Sizes
50UL
£ POA
ES11457-50UL
100UL
£ POA
ES11457-100UL
About this Product
- SKU:
- ES11457
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Chemokines are a group of small (approximately 8 to 14 kD); mostly basic; structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane; G protein-coupled receptors. Chemokines also play fundamental roles in the development; homeostasis; and function of the immune system; and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies; CXC and CC; based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al.; 2002 [PubMed 11821900])
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 120-200
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
