AMGO2 rabbit pAb
Product Sizes
50UL
£ POA
ES11318-50UL
100UL
£ POA
ES11318-100UL
About this Product
- SKU:
- ES11318
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.;similarity:Belongs to the immunoglobulin superfamily. AMIGO family.;similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.;similarity:Contains 6 LRR (leucine-rich) repeats.;subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.;subunit:Binds itself as well as AMIGO1 and AMIGO3.;tissue specificity:Highest levels in breast; ovary; cervix; and uterus. Lower levels in lung; colon; and rectum. Differentially expressed in 56% of thyroid; 57% of pancreatic and 45% of stomach cancers.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 270-350
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
