HBEGF rabbit pAb
Product Sizes
50UL
£ POA
ES11256-50UL
100UL
£ POA
ES11256-100UL
About this Product
- SKU:
- ES11256
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.;PTM:O-linked glycan attachment sites were determined by Edman degradation; O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).;PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63; 73 and 74 have been tested and found to be biologically active.;similarity:Contains 1 EGF-like domain.;subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 130-210
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
