LIGO1 rabbit pAb
Product Sizes
50UL
£ POA
ES11241-50UL
100UL
£ POA
ES11241-100UL
About this Product
- SKU:
- ES11241
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.;PTM:N-glycosylated. Contains predominantly high-mannose glycans.;similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.;similarity:Contains 13 LRR (leucine-rich) repeats.;subunit:Homotetramer. Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19.;tissue specificity:Expressed exclusively in the central nervous system. Highest level in the in amygdala; hippocampus; thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 370-450
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
