ROBO3 rabbit pAb
Product Sizes
50UL
£ POA
ES11128-50UL
100UL
£ POA
ES11128-100UL
About this Product
- SKU:
- ES11128
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth; growth cone guidance; and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3; a family of secreted chemorepellants; are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis; leukocyte migration; kidney morphogenesis; angiogenesis; and vasculogenesis in addition to neurogenesis. This gene; ROBO3; has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs; a transmembrane segment; and a cytoplasmic tail with three conserved signaling motifs: CC0; CC2; and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members; ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse; loss of R
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
