CFC1B rabbit pAb
Product Sizes
50UL
£ POA
ES10999-50UL
100UL
£ POA
ES10999-100UL
About this Product
- SKU:
- ES10999
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- disease:Defects in CFC1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects; such as tetralogy of Fallot; pulmonary atresia; double-outlet right ventricle; truncus arteriosus communis; and aortic arch anomalies.;disease:Defects in CFC1 are a cause of transposition of the great arteries; dextro-looped (DTGA) [MIM:608808]. The more common form of DTGA; consists of complete inversion of the great vessels; so that the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle. This creates completely separate pulmonary and systemic circulatory systems; an arrangement that is incompatible with life. Patients often have atrial and/or ventricular septal defects or other types of shunting that allow some mixing between the circulations in order to support life minimally; but surgical intervention is always required.;disease:Defects in CFC1 are a cause of visceral heterotaxy (HTX2) [MIM:605376]. HTX2 is an autosomal form of visceral heterotaxy (HTX). HTX is characterized by a variable group of congenital anomalies that include complex cardiac malformations and situs inversus or situs ambiguus.;function:Involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.;PTM:N-glycosylated.;similarity:Contains 1 EGF-like domain.;
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
