MEP1B rabbit pAb
Product Sizes
50UL
£ POA
ES10990-50UL
100UL
£ POA
ES10990-100UL
About this Product
- SKU:
- ES10990
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes; and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates; and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related; but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted; whereas; oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability; renal gene expression profiles; and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq; Oct 2011];
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
