CDO1 rabbit pAb
Product Sizes
50UL
£ POA
ES10948-50UL
100UL
£ POA
ES10948-100UL
About this Product
- SKU:
- ES10948
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:L-cysteine + O(2) = 3-sulfinoalanine.;cofactor:Binds 1 iron ion per subunit. Zinc to a much lesser extent.;cofactor:IRON; NAD(P)H.;function:Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate; hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.;induction:In hepatoblastoma HepG2 cells; down-regulated by phorbol 12-myristate 13-acetate.;pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.;PTM:The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion; and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.;similarity:Belongs to the cysteine dioxygenase family.;subunit:Monomer.;tissue specificity:Highly expressed in liver and placenta. Low expression in heart; brain and pancreas. Also detected in hepatoblastoma HepG2 cells.;
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
