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Antibodies

GPX3 rabbit pAb

Product Sizes
50UL
£ POA
ES10932-50UL
100UL
£ POA
ES10932-100UL
About this Product
SKU:
ES10932
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the glutathione peroxidase family; members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione; and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates; which vary in cellular location and substrate specificity. This isozyme is secreted; and is abundantly found in plasma. Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies; including thyroid cancer; hepatocellular carcinoma and chronic myeloid leukemia. This isozyme is also a selenoprotein; containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon; which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure; designa
Immunogen:
Synthesized peptide derived from part region of human protein
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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