P3C2B rabbit pAb
Product Sizes
50UL
£ POA
ES10786-50UL
100UL
£ POA
ES10786-100UL
About this Product
- SKU:
- ES10786
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation; oncogenic transformation; cell survival; cell migration; and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain; a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes; and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+; which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
