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Antibodies

MUL1 rabbit pAb

Product Sizes
50UL
£ POA
ES10762-50UL
100UL
£ POA
ES10762-100UL
About this Product
SKU:
ES10762
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
domain:The zinc finger domain is required for E3 ligase activity.;function:E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed; activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.;pathway:Protein modification; protein ubiquitination.;similarity:Contains 1 RING-type zinc finger.;subcellular location:Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.;subunit:Homooligomer. Interacts with MAP3K7/TAK1.;tissue specificity:Widely expressed with highest levels in the heart; skeletal muscle; placenta; kidney and liver. Barely detectable in colon and thymus.;
Immunogen:
Synthesized peptide derived from part region of human protein
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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