HIPK3 rabbit pAb
Product Sizes
50UL
£ POA
ES10650-50UL
100UL
£ POA
ES10650-100UL
About this Product
- SKU:
- ES10650
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;function:Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.;PTM:Autophosphorylated; but autophosphorylation is not required for catalytic activity.;PTM:May be sumoylated.;similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.;similarity:Contains 1 protein kinase domain.;subunit:Interacts with Nkx1-2. Interacts with FAS and DAXX. Probably part of a complex consisting of HIPK3; FAS and FADD. Interacts with and stabilizes ligand-bound androgen receptor (AR) (By similarity). Interacts with UBL1/SUMO-1.;tissue specificity:Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle; and at lower levels in placenta; pancreas; brain; spleen; prostate; thymus; testis; small intestine; colon and leukocytes. Not found in liver and lung.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 770-850
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
