CYFP1 rabbit pAb
Product Sizes
50UL
£ POA
ES10592-50UL
100UL
£ POA
ES10592-100UL
About this Product
- SKU:
- ES10592
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.;similarity:Belongs to the CYFIP family.;subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes; membrane ruffles and at the tips of lamellipodia.;subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1; CYFIP1/SRA1; NCKAP1/NAP1 and WASF2/WAVE2 (By similarity). Interacts through its C-terminus with the C-terminus of DPYSL2/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 980-1060
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
