CENPS rabbit pAb
Product Sizes
50UL
£ POA
ES10529-50UL
100UL
£ POA
ES10529-100UL
About this Product
- SKU:
- ES10529
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain; similar to that found in TATA box-binding protein-associated factor; TAF(II)31; which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors; and was shown to reduce cell growth in neuroblastoma cells; suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes; including the Fanconi anemia (FA) core complex; the APITD1/CENPS complex; and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex; and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 70-150
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
