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Antibodies

CDC42 rabbit pAb

Product Sizes
50UL
£ POA
ES10520-50UL
100UL
£ POA
ES10520-100UL
About this Product
SKU:
ES10520
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a small GTPase of the Rho-subfamily; which regulates signaling pathways that control diverse cellular functions including cell morphology; migration; endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42; and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP); which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3; 4; 5; 7; 8 and 20. [provided by RefSeq; Apr 2013];
Immunogen:
Synthesized peptide derived from human protein . at AA range: 80-160
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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