Cleaved-Lamin A (D230) rabbit pAb
Product Sizes
50UL
£ POA
ES1041-50UL
100UL
£ POA
ES1041-100UL
About this Product
- SKU:
- ES1041
- Additional Names:
- LMNA; LMN1; Prelamin-A/C
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis; the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability; chromatin structure and gene expression. Vertebrate lamins consist of two types; A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy; familial partial lipodystrophy; limb girdle muscular dystrophy; dilated cardiomyopathy; Charcot-Marie-Tooth disease; and Hutchinson-Gilford progeria syndrome. [provided by RefSeq; Apr 2012];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Lamin A. AA range:181-230
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
