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Antibodies

RPGF6 rabbit pAb

Product Sizes
50UL
£ POA
ES10095-50UL
100UL
£ POA
ES10095-100UL
About this Product
SKU:
ES10095
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:Guanine nucleotide exchange factor (GEF) for Rap1A; Rap2A and M-Ras GTPases. Does not interact with cAMP.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Contains 1 cyclic nucleotide-binding domain.;similarity:Contains 1 N-terminal Ras-GEF domain.;similarity:Contains 1 PDZ (DHR) domain.;similarity:Contains 1 Ras-associating domain.;similarity:Contains 1 Ras-GEF domain.;subcellular location:Upon binding to M-Ras; it translocates to the plasma membrane.;subunit:Interacts with the second PDZ domain of human PTP1e.;tissue specificity:Isoform 3 has highest expression levels in the brain; heart; liver; lung and placenta and is barely detectable in skeletal muscle; kidney and pancreas.;
Immunogen:
Synthesized peptide derived from human protein . at AA range: 460-540
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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