RPGF4 rabbit pAb
Product Sizes
50UL
£ POA
ES10094-50UL
100UL
£ POA
ES10094-100UL
About this Product
- SKU:
- ES10094
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.;domain:The N-terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2.;function:Guanine nucleotide exchange factor (GEF) for RAP1A; RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent; PKA-independent exocytosis through interaction with RIMS2.;similarity:Contains 1 DEP domain.;similarity:Contains 1 N-terminal Ras-GEF domain.;similarity:Contains 1 Ras-GEF domain.;similarity:Contains 2 cyclic nucleotide-binding domains.;subunit:Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A.;tissue specificity:Predominantly expressed in brain and adrenal gland. Isoform 2 is expressed in liver. Isoform 1 is expressed in liver at very low levels.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 240-320
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
