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Antibodies

PHC3 rabbit pAb

Product Sizes
50UL
£ POA
ES10019-50UL
100UL
£ POA
ES10019-100UL
About this Product
SKU:
ES10019
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:Component of the Polycomb group (PcG) multiprotein PRC1 complex; a complex required to maintain the transcriptionally repressive state of many genes; including Hox genes; throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119'; rendering chromatin heritably changed in its expressibility.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Contains 1 FCS-type zinc finger.;similarity:Contains 1 SAM (sterile alpha motif) domain.;subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110; BMI1/PCGF4; CBX2/M33; CBX4/PC2; CBX8/PC3; PHC1; PHC2; PHC3; SCMH1; RING1 and RNF2/RING2.;
Immunogen:
Synthesized peptide derived from human protein . at AA range: 720-800
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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