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Antibodies

PLEC rabbit pAb

Product Sizes
50UL
£ POA
ES10012-50UL
100UL
£ POA
ES10012-100UL
About this Product
SKU:
ES10012
Application:
Immunohistochemistry, Immunofluorescence
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Plectin is a prominent member of an important family of structurally and in part functionally related proteins; termed plakins or cytolinkers; that are capable of interlinking different elements of the cytoskeleton. Plakins; with their multi-domain structure and enormous size; not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape; but also serve as scaffolding platforms for the assembly; positioning; and regulation of signaling complexes (reviewed in PMID: 9701547; 11854008; and 17499243). Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055; 8698233). Until 2010; this locus was named plectin 1 (symbol PLEC1 in human; Plec1 in mouse and rat) and the gene product had been referred to as "hemidesmosomal protein 1" or &qu
Immunogen:
Synthesized peptide derived from human protein . at AA range: 240-320
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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