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Proteins and Peptides

Recombinant Mouse TGFBR2 (C-6His)

Product Sizes
50ug
£ POA
EPT293-50UG
About this Product
SKU:
EPT293
Additional Names:
TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II; Tgfbr2
Extra Details:
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development; cell proliferation; and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI); TGF-β receptor type II (TGF-β-RII); and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
Molecular Weight:
16.2 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
Supplier:
ELK Biotechnology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Endotoxin Level:
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
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