Recombinant Human CDH16 (C-6His)
Product Sizes
10ug
£ POA
EPT249-10UG
About this Product
- SKU:
- EPT249
- Additional Names:
- CDH16; Cadherin-16; Kidney-specific cadherin; Ksp-cadherin
- Extra Details:
- Cadherin-16(CDH16) is a single-pass type I membrane protein which contains six cadherin domains. Mature cadherin proteins consist of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium-dependent cell adhesion proteins and may contribute to the sorting of heterogeneous cell types. They preferentially interact with themselves in a homophilic manner in connecting cells. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections; imparting a strong curvature to the full-length ectodomain. CDH16 is exclusively expressed in kidney; where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development. CDH16 is composed of an extracellular domain containing 6 cadherin domains; a transmembrane region and a truncated cytoplasmic domain. However; it lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.
- Molecular Weight:
- 84.4 KDa
- Purity:
- Greater than 75% as determined by reducing SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Supplier:
- ELK Biotechnology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
