Recombinant Human CALM1
Product Sizes
50ug
£ POA
EPT236-50UG
About this Product
- SKU:
- EPT236
- Additional Names:
- Calmodulin; CaM; CALM1; CALM; CAM; CAM1; CALM2; CAM2; CAMB; CALM3; CALML2; CAM3; CAMC; CAMIII
- Extra Details:
- Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+; and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+; Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small; highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation; metabolism; apoptosis; smooth muscle contraction; intracellular movement; short-term and long-term memory; and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations; including the cytoplasm; within organelles; or associated with the plasma or organelle membranes; but it is always found intracellularly.
- Molecular Weight:
- 16.8 KDa
- Purity:
- Greater than 95% as determined by reducing SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Supplier:
- ELK Biotechnology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
