Recombinant Mouse Thrombomodulin (C-6His)
Product Sizes
10ug
£ POA
EPT230-10UG
About this Product
- SKU:
- EPT230
- Additional Names:
- Thrombomodulin; TM; Fetomodulin; CD141; BDCA-3; Thbd
- Extra Details:
- Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3); which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin; EGF-like; transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells; THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin; which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI); also known as carboxypeptidase B2 (CPB2). In addition; THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis; stroke; arteriosclerosis; and cancer.
- Molecular Weight:
- 54.6 KDa
- Purity:
- Greater than 95% as determined by reducing SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at ≤-70[o]C; stable for 6 months after receipt. Store at ≤-70[o]C; stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
- Supplier:
- ELK Biotechnology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
