Recombinant Human C3a
Product Sizes
50ug
£ POA
EPT178-50UG
About this Product
- SKU:
- EPT178
- Additional Names:
- Complement Component C3a; C3a; Anaphylatoxin
- Extra Details:
- Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical; alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase; which cleaves C3 into the key effector molecules; C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR); C3a exhibits potent anaphylatoxin activity; including increased vascular permeability; triggering degranulation of mast cells; inflammation; and activating leukocytes.
- Molecular Weight:
- 9.1 KDa
- Purity:
- Greater than 95% as determined by reducing SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Supplier:
- ELK Biotechnology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
