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Proteins and Peptides

Recombinant Mouse VEGF 164

Product Sizes
10ug
£ POA
EPT170-10UG
About this Product
SKU:
EPT170
Additional Names:
Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGFA164; VEGF164
Extra Details:
Mouse Vascular endothelial growth factor (VEGF or VEGF­A); is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120; 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt­1) and VEGF R2 (Flk­/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1; VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation; migration; and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation; when increased transport of molecules from the blood is required for efficient milk protein synthesis.
Molecular Weight:
19.27 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
Supplier:
ELK Biotechnology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Endotoxin Level:
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
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