Recombinant Human CHI3L2 (C-6His)
Product Sizes
50ug
£ POA
EPT164-50UG
About this Product
- SKU:
- EPT164
- Additional Names:
- Chitinase-3-Like Protein 2; Chondrocyte Protein 39; YKL-39; CHI3L2
- Extra Details:
- Chitinase 3-Like Protein 2 (CHI3L2) is a 39 kDa secreted glycoprotein which belongs to the glycosyl hydrolase 18 family and the most closely related to human cartilage glycoprotein 39; which promotes the growth of human synovial cells as well as skin and fetal lung fibroblasts. Highest expression of CHI3L2 is in chondrocytes; followed by synoviocytes; lung and heart. It is not detected in spleen; pancreas; and liver. CHI3L2 may also be expressed in developing brain and placenta. Increased levels of CHI3L2 have been demonstrated in synovial fluids of patients with rheumatoid or osteoarthritis as well as in some other pathologies and in malignant tumors; particularly in glioblastomas. CHI3L2 may bind glycan structure with high affinity; but not heparin. It has has no chitotriosidase activity; but is likely to bind some type of glycan.
- Molecular Weight:
- 41.94 KDa
- Purity:
- Greater than 95% as determined by reducing SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Supplier:
- ELK Biotechnology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
