Claudin-2 (8H11) Mouse mAb
Product Sizes
50UL
£ POA
EM1403-50UL
100UL
£ POA
EM1403-100UL
About this Product
- SKU:
- EM1403
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- The claudin family is composed of 23 integral membrane proteins; and their expression; which varies among tissue types; may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney; where it regulates transepithelial ion (e.g.; Na+; Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines ; including A549 lung adenocarcinoma cells; where its nuclear distribution was positively associated with enhanced proliferation .
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Monoclonal Antibody
