CD68 Mouse mAb
Product Sizes
50UL
£ POA
EM1162-50UL
100UL
£ POA
EM1162-100UL
About this Product
- SKU:
- EM1162
- Additional Names:
- CD68 molecule; GP110; Macrosialin; SCARD1
- Application:
- Immunohistochemistry
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages; Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages; both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins; allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Monoclonal Antibody
