COX2/Cyclooxygenase 2 Mouse mAb
Product Sizes
50UL
£ POA
EM1160-50UL
100UL
£ POA
EM1160-100UL
About this Product
- SKU:
- EM1160
- Additional Names:
- PTGS2 antibody; Prostaglandin H2 synthase 2 antibody; PGHS 2 antibody; Glucocorticoid-regulated inflammatory cyclooxygenase antibody
- Application:
- Immunohistochemistry
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- Prostaglandin-endoperoxide synthase 2; also known as cyclooxygenase-2 or simply COX-2; is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2; which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs; but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered; but their precise roles are yet to be described.
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Monoclonal Antibody
