NFkB p65 Mouse mAb
Product Sizes
50UL
£ POA
EM1111-50UL
100UL
£ POA
EM1111-100UL
About this Product
- SKU:
- EM1111
- Additional Names:
- NFKB3; p65; RELA; Transcription factor p65
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- NFkB p65 is ubiquitinated leading to its proteosomal degradation; which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP; enhancing transcriptional activity. NFkB p65 is also acetylated at K122; enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB; which coordinates various aspects of immune function required for resistance to infection.
- Immunogen:
- Recombinant Protein
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Monoclonal Antibody
