CK16 Mouse mAb
Product Sizes
50UL
£ POA
EM1056-50UL
100UL
£ POA
EM1056-100UL
About this Product
- SKU:
- EM1056
- Additional Names:
- Cytokeratin 16; K16; K1CP; keratin 16; KRT16; KRT16A; NEPPK
- Application:
- Immunohistochemistry
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- Keratin 16 is expressed in keratinocytes; which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly; a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins; but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation; and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Monoclonal Antibody
