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Antibodies

CD45 Mouse mAb

Product Sizes
50UL
£ POA
EM1046-50UL
100UL
£ POA
EM1046-100UL
About this Product
SKU:
EM1046
Additional Names:
B220; CD45R; GP180; L CA; LCA; Leukocyte common antigen; LY5; PTPRC; RPTPC; T200
Application:
Western Blot
Clonality:
Monoclonal
Concentration:
1mg/mL
Extra Details:
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction; inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.
Immunogen:
Synthetic Peptide
Isotype:
IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Source:
Mouse
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Monoclonal Antibody
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