EGFR Mouse mAb
Product Sizes
50UL
£ POA
EM1044-50UL
100UL
£ POA
EM1044-100UL
About this Product
- SKU:
- EM1044
- Additional Names:
- Epidermal Growth Factor Receptor ;ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog;Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF; TGFA/TGF-alpha; amphiregulin; epigen/EPGN; BTC/betacellulin; epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascadesβ-Actin is one of six different actin isoforms that have been identified. The actin molecules found in cells of various species and tissues tend to be very similar in their immunological and physical properties. Therefore; Antibodies against β-Actin are useful as loading controls for Western Blotting. However it should be noted that levels of β-Actin may not be stable in certain cells. For example; expression of β-Actin in adipose tissue is very low and therefore β-Actin should not be used as loading control for these tissues.
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Monoclonal Antibody
