HSP70 Mouse mAb
Product Sizes
50UL
£ POA
EM1042-50UL
100UL
£ POA
EM1042-100UL
About this Product
- SKU:
- EM1042
- Additional Names:
- Heat shock 70 kDa protein 1/2; heat shock 70kDa protein 1A; HSP70; HSP70 1; HSP70 1/HSP70 2; HSP70 1A; HSP70.1/HSP70.2; HSP70I; HSP72; HSPA1; HSPA1A; HSPA1B
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence
- Clonality:
- Monoclonal
- Concentration:
- 1mg/mL
- Extra Details:
- The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding; and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity; such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes; the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues; and interacts with them. This spontaneous interaction is reversible; and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However; the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70; increasing its normally slow rate of ATP hydrolysis.
- Immunogen:
- Synthetic Peptide
- Isotype:
- IgG1
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Mouse
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Monoclonal Antibody
