Calreticulin Rabbit pAb
Product Sizes
50UL
£ POA
EA366-50UL
100UL
£ POA
EA366-100UL
About this Product
- SKU:
- EA366
- Additional Names:
- CALR; Calregulin; cC1qR; CRP55; CRT; CRTC; ERp60; grp60; HACBP; RO; SSA
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1mg/mL
- Extra Details:
- Calcium is a universal signaling molecule involved in many cellular functions such as cell motility; metabolism; protein modification; protein folding; and apoptosis. Calcium is stored in the endoplasmic reticulum (ER); where it is buffered by calcium binding chaperones such as calnexin and calreticulin; and is released via the IP3 Receptor channel . Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such; calreticulin presumably does not alter protein folding but regulates proper timing for efficient folding and subunit assembly. Furthermore; calreticulin retains proteins in non-native conformation within the ER and targets them for degradation .
- Immunogen:
- Recombinant Protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
