MEK4 (F194)Rabbit pAb
Product Sizes
50UL
£ POA
EA362-50UL
100UL
£ POA
EA362-100UL
About this Product
- SKU:
- EA362
- Additional Names:
- JNK activating kinase 1; JNKK; JNKK1; MAP kinase kinase 4; MAP2K4; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MKK4; PRKMK4; SAPK/ERK kinase 1; SEK1; SERK1
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1mg/mL
- Extra Details:
- SAPK/Erk kinase (SEK1); also known as MEK4 or MKK4 or Jun kinase kinase (JNKK); activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines . Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261; respectively. Like MEK; SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop . Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction .
- Immunogen:
- Recombinant Protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
