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Antibodies

SOX2 Monoclonal Antibody

Product Sizes
0.2 ml
£383.00
ELAB6940-R-0.2ML
1 ml
£1410.00
ELAB6940-R-1ML
About this Product
SKU:
ELAB6940-R
Additional Names:
SOX2
Application:
IHC-Paraffin
translate.label.attr.clone:
YN02195r
Clonality:
Monoclonal
Extra Details:
The SOX2 gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors, which plays an important role in early organ development. SOX2 can be used in the auxiliary diagnosis of germ cell tumors. 90% of embryonic cancers express SOX2, but not in seminoma, yolk sac tumor and choriocarcinoma. SOX2 has been shown to be a negative prognostic factor and associated with aggressive phenotypes in breast, head and neck, gastric, colorectal and bladder cancers. In small cell lung cancers, SOX2 was also correlated with a poor prognosis. Conversely, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and was shown to be an independent positive prognostic marker.
Host:
Rabbit
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody