QuicKey Pro Mouse EGFR (Epidermal Growth Factor Receptor) ELISA Kit
Product Sizes
24 tests
£143.00
E-OSEL-M0021-24TESTS
48 tests
£307.00
E-OSEL-M0021-48TESTS
96 tests
£371.00
E-OSEL-M0021-96TESTS
About this Product
- SKU:
- E-OSEL-M0021
- Additional Names:
- ErbB-1,ErbB1,ERBB
- Application:
- ELISA
- Extra Details:
- Epidermal Growth Factor Receptor (EGFR) is a receptor tyrosine kinase that links extracellular mitogenic ligand binding to complex downstream signaling cascades. Initial ligand binding results in receptor oligomerization and autophosphorylation of multiple tyrosine residues within cytosolic domains of the the protein. These phosphorylation events stabilize the EGFR kinase activation loop and lead to the recruitment of adaptor proteins and other downstream effectors. EGFR stimulation leads to activation of RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCG Gamma-PKC and STAT signaling cascades, and constitutive activation of the receptor promotes tumorigenesis in multiple cancers.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 0.16-10 ng/mL
- Reactivities:
- Mouse
- Sensitivity:
- 0.09 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-quickey_pro_mouse_egfr_(epidermal_growth_factor_receptor)_elisa_kit-e_osel_m0021
