Mini Sample Mouse CEACAM1 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 1) ELISA Kit
Product Sizes
24 tests
£143.00
E-MSEL-M0124-24TESTS
48 tests
£302.00
E-MSEL-M0124-48TESTS
96 tests
£365.00
E-MSEL-M0124-96TESTS
About this Product
- SKU:
- E-MSEL-M0124
- Additional Names:
- Cell adhesion molecule CEACAM1,Biliary glycoprotein 1 ,BGP-1,Biliary glycoprotein D,Carcinoembryonic antigen-related cell adhesion molecule 1,MHVR1,Murine hepatitis virus receptor,MHV-R,CD66a,Bgp,Bgp1
- Application:
- ELISA
- Extra Details:
- Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner.Plays a role as coinhibitory receptor in immune response, insulin action and also functions as an activator during angiogenesis.Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors.Plays a role in immune response, of T-cells, natural killer (NK) and neutrophils.Upon TCR/CD3 complex stimulation, inhibits TCR-mediated cytotoxicity by blocking granule exocytosis by mediating homophilic binding to adjacent cells, allowing interaction with and phosphorylation by LCK and interaction with the TCR/CD3 complex which recruits PTPN6 resulting in dephosphorylation of CD247 and ZAP70.Also inhibits T-cell proliferation and cytokine production through inhibition of JNK cascade and plays a crucial role in regulating autoimmunity and anti-tumor immunity by inhibiting T-cell through its interaction with HAVCR2.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 5.47-350 pg/mL
- Reactivities:
- Mouse
- Sensitivity:
- 3.28 pg/mL
- Shipping Conditions:
- Blue Ice
- Specificity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-mini_sample_mouse_ceacam1_(carcinoembryonic_antigen_related_cell_adhesion_molecule_1)_elisa_kit-e_msel_m0124
