Mini Sample Human GDF15 ( Growth Differentiation Factor 15 ) ELISA Kit
Product Sizes
24 tests
£143.00
E-MSEL-H0014-24TESTS
48 tests
£302.00
E-MSEL-H0014-48TESTS
96 tests
£365.00
E-MSEL-H0014-96TESTS
About this Product
- SKU:
- E-MSEL-H0014
- Additional Names:
- MIC-1,NAG-1,pTGFB,PDF,PLAB
- Application:
- ELISA
- Extra Details:
- GDF-15 is a member of the TGF-B Beta superfamily. GDF-15 is expressed as a 308 amino acids precursor that includes a signal peptide, a pro-domain, and a 112 residue mature protein. The secreted pro-domain binds to the extracellular matrix, where it can be activated by multiple enzymes such as furin (PCSK3), PCSK5, PCSK6, MMP-26, and MT1-MMP. GDF-15 is mainly expressed in placenta and prostate. Its expression is low in other tissues such as kidney, bladder, stomach, pancreas, liver, and gall bladder. GDF-15 is highly expressed in cancer cells with high levels detected in serum of cancer patients. GDF-15 has an important role in metabolic syndrome. GDF-15 transgenic mice present a lean phenotype. Furthermore, GDF-15 affects the macrophages in adipose tissue.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 62.5-4000 pg/mL
- Reactivities:
- Human
- Sensitivity:
- 37.5 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-mini_sample_human_gdf15 _(_growth_differentiation_factor_15_)_elisa_kit-e_msel_h0014
