Mouse GAL3 Antibody Pair Set
Product Sizes
1 set
£882.00
E-KAB-0690-1SET
About this Product
- SKU:
- E-KAB-0690
- Additional Names:
- LGALS3,CBP35,GALBP,GALIG,L31,LGALS2,MAC2,Lectin,Galactoside-Binding Soluble 3
- Application:
- ELISA
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Extra Details:
- Galectin-3 is a member of the lectin family,which includes 15 mammalian lectin members. Like all galectins,galectin-3 contains a carbohydrate recognition binding domain of about 130 amino acids that enables the specific binding of B Beta-galactosides. This protein has been shown to be involved in cell adhesion,cell activation,chemoattraction,cell growth and differentiation,cell cycle,and apoptosis. Galectin-3 induces pro-inflammatory cytokines and inhibits Th2 type cytokine production. It chemoattracts monocytes and macrophages,and activates and degranulates basophils and mast cells. Galectin-3 has been shown to be involved in cancer,inflammation,fibrosis,heart disease,and stroke. It has also been shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure,including myofibroblast proliferation,tissue repair,inflammation,fibrogenesis,and ventricular remodeling. In addition,galectin-3 was found to contribute to tumor cell evasion of the immune system. Galectin-3 is increasingly being used as a diagnostic marker for different cancers. It can be screened for and used as a prognostic factor to predict the progression of the cancer.
- Format:
- Colorimetric method;ELISA;Sandwich
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- GAL3
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Antibody Pair
- Manufacturer's Data Sheet:p-mouse_gal3_antibody_pair_set-e_kab_0690
