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Antibodies

Human AR Antibody Pair Set

Product Sizes
1 set
£882.00
E-KAB-0676-1SET
About this Product
SKU:
E-KAB-0676
Additional Names:
AREG,CRDGF,SDGF
Application:
ELISA
Buffer:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Extra Details:
Amphiregulin was initially identified in the conditioned medium of human mammary gland MCF-7 cells treated with TPA. The mouse gene was cloned from the androgen-dependent SC2G cell line derived from Shionogi mouse mammary carcinoma SC115. It belongs to the EGF family of proteins that includes EGF,TGF-A Alpha,heparin-binding EGF like-growth factor (HB-EGF),epigen,epiregulin,and betacellulin. Mouse amphiregulin is derived from a 248 amino acid transmembrane precursor and it has 66% identity to the human protein. All the EGF family members are synthesized as type I membrane protein precursors,which can undergo proteolytic cleavage at the plasma membrane to release a mature soluble ectodomain. ADAM17 (TACE) has an important role in ectodomain shedding of amphiregulin,TNF-A Alpha,and HB-EGF.
Format:
Colorimetric method;ELISA;Sandwich
Formulation:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:
AR
Physical State:
Other Biological Fluid, Plasma, Serum
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Antibody Pair