Human IL-3 Antibody Pair Set
Product Sizes
1 set
£882.00
E-KAB-0675-1SET
About this Product
- SKU:
- E-KAB-0675
- Additional Names:
- IL3,MCGF,MCSF,MULTI-CSF,P-Cell Stimulating Factor
- Application:
- ELISA
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Extra Details:
- Interleukin-3 (lL-3) is a hemopoietic growth factor involved in the survival,proliferation,and differentiation of multipotent hemopoietic cells. In addition to granulocyte-macrophage colony-stimulating factor (GMCSF) and IL-5,IL-3 is the most potent growth factor for basophils. On mature basophils,these three cytokines act through specific receptors mediating adhesion,migration,and releasability. Mast cells expresses high amounts of IL-3. In the absence of antigen,rapid release of large amount of IL-3 in an autocrine dependent manner is responsible for mast cell survival. IL-3 plays a vital role in stimulating basophils and mast cell responses to parasite infections. IL-3 has also been implicated in the pathogenesis of several chronic inflammatory diseases,including asthma,atherosclerosis,and neurodegenerative disorders,such as multiple sclerosis. IL-3 stimulates colony formation of megakaryocytes,neutrophils,and macrophages from bone marrow cultures. IL-3 is expressed in the major embryonic vessels and regulates the survival and proliferation of hematopoietic stem cells in the early stages of embryonic development.
- Format:
- Colorimetric method;ELISA;Sandwich
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- IL-3
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Antibody Pair
- Manufacturer's Data Sheet:p-human_il_3_antibody_pair_set-e_kab_0675
