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Antibodies

Rat IL-6R Antibody Pair Set

Product Sizes
1 set
£882.00
E-KAB-0652-1SET
About this Product
SKU:
E-KAB-0652
Additional Names:
IL6R,CD126,IL-6R-1,IL-6R-Alpha,IL6Q,IL6RA,IL6RQ,gp80
Application:
ELISA
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Extra Details:
Part of the receptor for interleukin 6. Binds to IL6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling',the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
Format:
Colorimetric method;ELISA;Sandwich
Formulation:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
IL-6R
Physical State:
Other Biological Fluid, Plasma, Serum
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Antibody Pair