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Antibodies

Human A Alpha2-M Antibody Pair Set

Product Sizes
1 set
£512.00
E-KAB-0526-1SET
About this Product
SKU:
E-KAB-0526
Additional Names:
A Alpha2M,A2M
Application:
ELISA
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Extra Details:
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases , including trypsin , thrombin and collagenase. It can also inhibit inflammatory cytokines , and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer&apos,s disease ( AD ) due to its ability to mediate the clearance and degradation of A-beta , the major component of beta-amyloid deposits. A related pseudogene , which is also located on the p arm of chromosome 12 , has been identified.
Format:
Colorimetric method;ELISA;Sandwich
Formulation:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
α2-M
Physical State:
Other Biological Fluid, Plasma, Serum
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Antibody Pair