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Antibodies

Human CASP4 Antibody Pair Set

Product Sizes
1 set
£512.00
E-KAB-0492-1SET
About this Product
SKU:
E-KAB-0492
Additional Names:
Caspase-4,CASP-4,ICE and Ced-3 homolog 2,ICH-2,ICE ( rel ) -II,Mih1,Protease TX,ICH2,TX
Application:
ELISA
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Extra Details:
This gene encodes a member of the cysteine proteases that plays important roles in apoptosis , cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is ",caspase 4 , apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
Format:
Colorimetric method;ELISA;Sandwich
Formulation:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
CASP4
Physical State:
Other Biological Fluid, Plasma, Serum
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Antibody Pair