Human TNFRSF1A Antibody Pair Set
Product Sizes
1 set
£512.00
E-KAB-0216-1SET
About this Product
- SKU:
- E-KAB-0216
- Additional Names:
- TNFRSF1A,CD120a,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR55,TNFR60,p55,p55-R,p60,TNFARMGC19588,TNF-R1,TNFR1TBP1,TNFRI,TNFR-I,CD120a antigen,TNF RI,tumor necrosis factor binding protein 1,Tumor necrosis factor receptor 1,tumor necrosis factor receptor 1A isoform beta,tumor necrosis factor receptor superfamily member 1A,tumor necrosis factor receptor type 1,Tumor necrosis factor receptor type I,tumor necrosis factor-alpha receptor,TNF-RI
- Application:
- ELISA
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Conjugate:
- Biotin
- Extra Details:
- Tumor necrosis factor (TNF) is a multifunctional cytokine that plays a key role in regulating inflammation,immune functions,host defense,and apoptosis . TNF exists in soluble and membrane-bound forms. TNF signals through two distinct cell surface receptors,TNFR1 (TNFRSF1A,CD120a) and TNFR2 (TNFRSF1B,CD120b). Whereas TNFR1 is widely expressed,expression of TNFR2 is limited to cells of the immune system,endothelial cells,and nerve cells . TNFR1,which contains a death domain (DD) within its intracytoplasmic region,is thought to be the key receptor for TNF signaling . This receptor can activate NF-kappaB,mediate apoptosis,and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor,and thus play regulatory roles in the signal transduction mediated by the receptor.
- Format:
- Colorimetric method;ELISA;Sandwich
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- TNFRSF1A
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Antibody Pair
- Manufacturer's Data Sheet:p-human_tnfrsf1a_antibody_pair_set-e_kab_0216
