Human IL-17A Antibody Pair Set
Product Sizes
1 set
£512.00
E-KAB-0115-1SET
About this Product
- SKU:
- E-KAB-0115
- Additional Names:
- IL17A,CTLA-8,CTLA8,IL-17,IL-17A,IL17,Interleukin-17A,Cytotoxic T-lymphocyte-associated antigen 8
- Application:
- ELISA
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Conjugate:
- Biotin
- Extra Details:
- IL17A,also named as IL-17,is a proinflammatory cytokine. IL-17,synthesized only by memory T cells and natural killer cells,has pleiotropic effects,mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2),as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis,psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein,that is widely expressed on epithelial cells,fibroblasts,B and T cells,and monocytic cells. In psoriatic skin lesions,both Th17 cells and their downstream effector molecules,e.g. IL-17 and IL-22,are highly increased.
- Format:
- Colorimetric method;ELISA;Sandwich
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- IL-17A
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Antibody Pair
- Manufacturer's Data Sheet:p-human_il_17a_antibody_pair_set-e_kab_0115
