Mouse IL-17C (Interleukin 17C) ELISA Kit
Product Sizes
24 tests
£134.00
E-EL-M3131-24TESTS
48 tests
£311.00
E-EL-M3131-48TESTS
96 tests
£377.00
E-EL-M3131-96TESTS
About this Product
- SKU:
- E-EL-M3131
- Additional Names:
- Interleukin-17C,Il-17c,Cytokine CX2
- Application:
- ELISA
- Extra Details:
- IL-17C(Interleukin 17C) is a pro-inflammatory cytokine that plays a crucial role in epithelial innate immunity, especially against intestinal bacterial pathogens, acting in an autocrine manner. It stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense via activating the NFKB and MAPK signaling pathways. It acts synergistically with IL22, TNF and IL1B to induce antibacterial peptides. It may exert a protective effect by maintaining epithelial homeostasis after inflammatory challenges, such as intestinal inflammation in a dextran sulfate sodium-induced colitis model. It can also promote an inflammatory phenotype, e.g., in psoriatic skin. Enhanced IL17C/IL17RE signaling may increase susceptibility to autoimmune diseases like autoimmune encephalitis.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 15.63-1000 pg/mL
- Reactivities:
- Mouse
- Sensitivity:
- 9.38 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-mouse_il_17c_(interleukin_17c)_elisa_kit-e_el_m3131
